Ajuda com PHP Fatal error: Uncaught exception 'PDOException' with message 'SQLSTATE[28000]

Olá, poderiam me ajudar com o erro abaixo?

[29-Oct-2018 10:05:04 America/Recife] PHP Fatal error: Uncaught exception 'PDOException' with message 'SQLSTATE[28000] [1045] Access denied for user 'mdoria'@'localhost' (using password: NO)' in /home/includes/conexao.php:22
Stack trace:
#0 /home/includes/conexao.php(22): PDO->__construct('mysql:host=loca...', NULL, NULL)
#1 /home/includes/connection.php(34): include('/home/mdoria/pu...')
#2 /home/functions_ajax.php(2): include('/home/mdoria/pu...')
#3 {main}
thrown in /home/includes/conexao.php on line 22

Meu php está com a seguinte estrutura:

Arquivo: connection.php

<?php
error_reporting(E_ALL & ~E_DEPRECATED & ~E_NOTICE);
date_default_timezone_set("America/Recife");

session_start();

include "includes/constantes.php";

include "includes/conexao.php";

	Arquivo: **conexao.php**

<?php
$conCore = new PDO("mysql:host=" . SERVIDOR . ";dbname=" . CORE_BANCO, CORE_USUARIO, CORE_SENHA);
$conCore->setAttribute(PDO::ATTR_ERRMODE, PDO::ERRMODE_EXCEPTION);

$conCore->query("SET NAMES 'utf8'");
$conCore->query('SET character_set_connection=utf8');
$conCore->query('SET character_set_client=utf8');
$conCore->query('SET character_set_results=utf8');

$query = "SELECT * FROM usuario WHERE identificador = '$_GET[sis]'";
$resultCore = $conCore->query($query);
$rowCore = $resultCore->fetch(PDO::FETCH_OBJ);

if (empty($rowCore->id)) {

	echo "<script>window.location.href = '$URLbase';</script>";
}

define("BANCO", $rowCore->banco);
define("USUARIO", $rowCore->user);
define("SENHA", $rowCore->senha);

$con = new PDO("mysql:host=" . SERVIDOR . ";dbname=" . BANCO, USUARIO, SENHA);
$con->setAttribute(PDO::ATTR_ERRMODE, PDO::ERRMODE_EXCEPTION);

$con->query("SET NAMES 'utf8'");
$con->query('SET character_set_connection=utf8');
$con->query('SET character_set_client=utf8');
$con->query('SET character_set_results=utf8');

	 

	Já antecipo meus agradecimentos a quem possa me auxiliar.